### Iowa State Cyclones and Mississippi State Bulldogs Face Off in Sioux Falls The No. 16 Iowa State Cyclones are set to compete against the Mississippi State Bulldogs at the Sanford Pentagon in Sioux Falls, South Dakota, on November 10, 2025. This matchup marks the first meeting of the season for both teams, with Iowa State entering the game with a record of 2-0 after victories over Fairleigh Dickinson University (FDU) and Grambling State, while Mississippi State comes in at 1-0 following a win against North Alabama [https://bluewaterhealthyliving.com/news/national-news/iowa/iowa-state-basketball-vs-mississippi-state-prediction-game-preview-3-things-to-watch][https://apnews.com/article/mississippi-state-bulldogs-iowa-state-cyclones-sioux-falls-college-basketball-mens-college-basketball-ac7c9117dcbe40e19d67054684cca152]. ### Breakdown of the Game's Context and Structure 1. **Team Performance**: - Iowa State has shown strong early-season form with two convincing wins. - Mississippi State is also coming off a solid victory, indicating both teams are in good shape. 2. **Game Location and Timing**: - The game will take place at a neutral site, the Sanford Pentagon, at 7 p.m. CT. - This setting may influence the dynamics of the game, as neither team has a home-court advantage. 3. **Player Highlights**: - Iowa State features three players on the Naismith Award preseason watchlist, showcasing their talent and potential impact on the game [https://si.com/college/mississippistate/basketball/how-to-watch-mississippi-state-basketball-vs-no-16-iowa-state]. 4. **Betting Insights**: - Analysts are providing predictions and betting breakdowns, indicating a competitive matchup that could be closely contested [https://statsalt.com/free-picks/college-basketball/mississippi-state-bulldogs-vs-iowa-state-cyclones-prediction-and-picks-november-10-2025][https://winnersandwhiners.com/free-picks/college-basketball/mississippi-state-vs-iowa-state-odds-preview-picks-prediction-november-10-2025]. ### Supporting Evidence and Data - **Iowa State's Record**: - 2-0, with wins against FDU and Grambling State. - **Mississippi State's Record**: - 1-0, with a victory over North Alabama by 24 points. - **Game Timing**: - Scheduled for 7 p.m. CT on November 10, 2025. - **Player Recognition**: - Three Iowa State players are on the Naismith Award watchlist, indicating high expectations for their performance [https://bluewaterhealthyliving.com/news/national-news/iowa/iowa-state-basketball-vs-mississippi-state-prediction-game-preview-3-things-to-watch][https://si.com/college/mississippistate/basketball/how-to-watch-mississippi-state-basketball-vs-no-16-iowa-state]. ### Conclusion and Key Takeaways In summary, the upcoming game between the No. 16 Iowa State Cyclones and the Mississippi State Bulldogs promises to be an exciting matchup. 1. **Iowa State's Strong Start**: The Cyclones are looking to maintain their unbeaten streak and capitalize on their early-season momentum. 2. **Mississippi State's Challenge**: The Bulldogs aim to prove their worth against a ranked opponent after a solid opening game. 3. **Neutral Site Dynamics**: Playing at the Sanford Pentagon may level the playing field, making for a competitive encounter. 4. **Player Impact**: The presence of standout players from Iowa State could be a decisive factor in the game's outcome. This game is not only significant for both teams' records but also sets the tone for the rest of the season as they navigate through their respective schedules [https://apnews.com/article/mississippi-state-bulldogs-iowa-state-cyclones-sioux-falls-college-basketball-mens-college-basketball-ac7c9117dcbe40e19d67054684cca152][https://bluewaterhealthyliving.com/news/national-news/iowa/where-to-watch-iowa-state-vs-mississippi-state-today-time-tv-for-college-basketball-game].