### FDA Issues Nationwide Recall of Prazosin Hydrochloride Due to Cancer Risk The U.S. Food and Drug Administration (FDA) has announced a significant recall of over 580,000 bottles of prazosin hydrochloride, a medication commonly prescribed for high blood pressure and post-traumatic stress disorder (PTSD). This recall, initiated by Teva Pharmaceuticals USA, stems from concerns that the medication may contain elevated levels of nitrosamine impurities, which are classified as potential carcinogens. The FDA has categorized this recall as a Class II risk, indicating that the use of the affected medication may lead to temporary or medically reversible adverse health consequences, or where the probability of serious adverse health consequences is remote [https://apnews.com/article/fda-recall-prazosin-teva-blood-cancer-ce6338047a5f628300cc95e0eeb89b0b]. ### Breakdown of the Recall and Its Implications 1. **Scope of the Recall**: - Teva Pharmaceuticals USA has voluntarily recalled **580,844 bottles** of prazosin hydrochloride capsules due to contamination concerns [https://www.forbes.com/sites/brucelee/2025/10/31/fda-once-again-a-blood-pressure-medication-recall-for-cancer-concerns]. - The recall affects various lots of the medication distributed across the United States [https://www.wsls.com/business/2025/10/31/fda-recalls-blood-pressure-medicine-tainted-with-cancer-causing-chemical]. 2. **Health Risks**: - The primary concern is the presence of **nitrosamine impurities**, which are known to be potentially cancer-causing [https://www.nbcconnecticut.com/news/health/580k-bottles-of-blood-pressure-medication-recalled-over-high-levels-of-cancer-causing-chemical/3658482]. - Patients using this medication are advised to consult their healthcare providers for alternatives and to check if their prescriptions are affected [https://www.abc15.com/life/recalls/half-a-million-bottles-of-blood-pressure-drug-recalled-for-high-carcinogen-levels]. 3. **Regulatory Response**: - The FDA has classified this recall as **Class II**, indicating a moderate risk to health [https://www.procapitas.com/news/world/fda-recalls-over-580000-bottles-of-blood-pressure-medication]. - The agency continues to monitor the situation and has urged manufacturers to ensure the safety and quality of their products [https://www.usatoday.com/story/news/health/2025/10/29/blood-pressure-medicine-recalled-prazosin-hydrochloride/86966059007]. ### Supporting Evidence and Data - **Recall Statistics**: - Total bottles recalled: **580,844** [https://www.forbes.com/sites/brucelee/2025/10/31/fda-once-again-a-blood-pressure-medication-recall-for-cancer-concerns]. - The recall was prompted by tests revealing **higher-than-acceptable levels** of a carcinogenic substance [https://www.timesnownews.com/world/us/us-news/prazosin-hydrochloride-blood-pressure-medication-recalled-over-cancer-causing-chemical-article-153077822]. - **Health Advisory**: - Patients are encouraged to return any affected medications to their pharmacy and consult with healthcare professionals regarding alternative treatments [https://www.livenowfox.com/news/blood-pressure-medication-recalled-due-cancerous-chemical]. ### Conclusion: Key Takeaways from the Prazosin Recall 1. **Significant Recall**: Over **580,000 bottles** of prazosin hydrochloride have been recalled due to potential cancer risks associated with nitrosamine impurities. 2. **Health Risks**: The FDA has classified the recall as Class II, indicating a moderate health risk, and patients are advised to seek alternatives. 3. **Regulatory Oversight**: The FDA is actively monitoring the situation and has emphasized the importance of drug safety and quality. In summary, the recall of prazosin hydrochloride capsules highlights critical concerns regarding medication safety and the potential health risks posed by contaminants. Patients should remain vigilant and consult healthcare providers to ensure their treatment remains safe and effective [https://www.thehealthy.com/news/more-than-580000-blood-pressure-drugs-recalled-nationwide-for-possible-cancer-causing-impurities].