### Louisville's Historic Upset: Cardinals Defeat No. 2 Miami with Stellar Defense - In a remarkable display of skill and strategy, the Louisville Cardinals achieved a stunning 24-21 victory over the second-ranked Miami Hurricanes on October 17, 2025. This win not only marked a significant upset but also ended Miami's impressive 10-game home winning streak. Louisville's defense was pivotal, intercepting Miami quarterback Carson Beck four times, including a crucial interception in the final minute while Miami was in field-goal range. The Cardinals jumped to an early 14-0 lead and maintained control throughout the game, showcasing their resilience and tactical prowess under head coach Jeff Brohm. This victory is particularly noteworthy as it snapped Louisville's 0-18 record against Top 10 teams in true road games, potentially positioning them for a spot in the AP Top 25 rankings [https://apnews.com/article/louisville-miami-score-6c0dd4aa546672e14aeac6acaa51fb23]. ### Breakdown of the Game's Key Elements 1. **Game Overview** - Louisville's victory over Miami was characterized by a strong defensive performance, particularly through interceptions. - The Cardinals took an early lead and never trailed, demonstrating effective game management. 2. **Player Performances** - Quarterback Miller Moss contributed significantly with two touchdown passes and a rushing touchdown. - Carson Beck, Miami's star quarterback, struggled with four interceptions, which proved detrimental to his team's chances. 3. **Statistical Highlights** - Louisville's defense limited Miami to just 63 rushing yards. - The Cardinals' offense was led by Chris Bell, who caught nine passes for 136 yards and two touchdowns. 4. **Historical Context** - This victory is Louisville's second-ever win against a top-two team in the Associated Press rankings. - The last time Miami lost at home was also to Louisville in 2023, highlighting a trend in their matchups. ### Supporting Data and Statistics - **Key Game Statistics:** - **Final Score:** Louisville 24, Miami 21 - **Interceptions:** Carson Beck (Miami) - 4 - **Passing Performance:** Beck completed 25 of 35 passes for 271 yards. - **Rushing Performance:** Louisville held Miami to 63 rushing yards, while their own running back Isaac Brown rushed for 113 yards on 15 carries. - **Touchdowns:** Miller Moss (Louisville) - 3 total (2 passing, 1 rushing) [https://www.sportingnews.com/us/ncaa-football/miami/news/louisville-shocks-no-2-miami-24-21-carson-beck-throws-four-interceptions/e7803d8d6158c585cf0acffa]. ### Conclusion: A Turning Point for Louisville - **Major Findings:** 1. **Defensive Dominance:** Louisville's defense was the cornerstone of their victory, effectively neutralizing Miami's offensive threats. 2. **Offensive Efficiency:** The Cardinals capitalized on their opportunities, with Moss leading a balanced offensive attack. 3. **Historical Significance:** This win not only boosts Louisville's confidence but also alters the landscape of college football rankings, potentially elevating them into the AP Top 25. - The Cardinals' performance against Miami signifies a pivotal moment in their season, showcasing their potential to compete at a higher level in college football [https://www.nytimes.com/athletic/6727631/2025/10/17/louisville-miami-score-result].