La Liga is the top professional football division of the Spanish football league system. Real Madrid, the defending champions, faced Real Betis in a match that would impact their position in the league standings. The match resulted in a setback for Real Madrid's title defense. - Real Madrid was defeated by Real Betis with a score of 2-1. - Isco Alarcón, a former Real Madrid player, scored the decisive goal for Real Betis. - The loss prevents Real Madrid from taking the top spot in La Liga. - Atletico Madrid now leads La Liga after their win against Athletic Bilbao. - The match took place in Seville, Spain.